Nucleosides and Analogues
Medchemexpress LLC Mtb ATP synthase-IN-1 | 2642394-38-3 | 98.55% | 323.30 | 1 ML
Mtb ATP synthase-IN-1 (compound 6ab) is a potent Mycobacterium tuberculosis (Mtb) ATP synthase inhibitor. It is identified for use as laboratory chemicals and in the manufacture of substances. This product is intended for research use only and should be handled by experienced personnel in appropriately equipped and authorized facilities.
- Potent Mtb ATP synthase inhibitor
- MIC of 0.452-0.499 μg/mL against Mtb
- Good metabolic stability
- Low cytotoxicity (Vero IC50 > 64 μg/mL)
- Acceptable oral bioavailability
- Suitable for researching anti-mycobacterium
- For research use only
Medchemexpress LLC Adenosine receptor inhibitor 2 | 2550401-76-6 | 99.1% | 406.28 | 1 MG
This compound is a potent adenosine receptor (AR) inhibitor, demonstrating dual affinity for A1 and A2A ARs. It exhibits higher affinity for the A1AR compared to the A2AAR.
- Potent AR inhibitor
- Dual affinity for A1 and A2A ARs
- Ki values: 52.2 nM for A1AR and 167 nM for A2AAR
- For research use only
Medchemexpress LLC Alpha-Guanosine | 15398-66-0 | C10H13N5O5 | 25 MG
Alpha-Guanosine is a purine nucleoside analog that exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC Adenosine 5'-triphosphate(ATP)-d4 ammonium salt | 2483831-82-7 | C10H24D4N9O13P3 | 1.16 MG
Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) is the deuterium labeled Adenosine 5'-triphosphate(ATP) ammonium salt. It is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Adenosine monophosphate | 61-19-8 | 99.8% | C10H14N5O7P | 1 ML
Adenosine monophosphate (AMP) is an adenosine A1 receptor agonist and a key cellular metabolite involved in regulating energy homeostasis and signal transduction. It demonstrates significant antiviral activity against HSV-1 and HSV-2.
- Acts as an adenosine A1 receptor agonist
- Demonstrates significant antiviral activity against HSV-1 and HSV-2
- Functions as a key cellular metabolite regulating energy homeostasis and signal transduction
- Shows negligible cell toxicity at 25 to 400 μM in RAW264.7 cells
- Significantly attenuates mRNA expression of TNF-α and IL-6 in RAW264.7 cells
- Reduces recruitment of NF-κB p65 to TNF-α, IL-6, and IL-1β gene promoters
- Increases hepatic adenosine levels in C57BL/6J mice
- Improves survival rate and lowers serum AST and ALT levels in treated mice
- Attenuates necrosis and reduces infiltration of inflammatory cells in vivo
Medchemexpress LLC Adenosine 3',5'-diphosphate disodium | 75431-54-8 | 99.1% | 471.16 | 1 MG
Adenosine 3',5'-diphosphate disodium is an hydroxysteroid sulfotransferases inhibitor. It is for research use only and not sold to patients.
- Hydroxysteroid sulfotransferases inhibitor
- For research use only
- Not sold to patients
- Soluble in H2O at ≥ 25 mg/mL (53.06 mM)
- Store at -20°C, sealed, away from moisture
- In solvent, store at -80°C (6 months) or -20°C (1 month), sealed, away from moisture
Medchemexpress LLC 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl- | 26578-09-6 | 98.0% | 283.24 | 250 MG
L-Guanosine is the L-configuration of Guanosine. This purine nucleoside exhibits anti-herpesvirus activity and can be used in the preparation of supramolecular hydrogel.
- L-configuration of guanosine
- Purine nucleoside
- Exhibits anti-herpesvirus activity
- Can be used in the preparation of supramolecular hydrogel
- Functions as a nucleoside antimetabolite/analog
- Acts as an inhibitor