Nucleosides and Analogues
Medchemexpress LLC β-nicotinamide mononucleotide, reduced form disodium | 108347-85-9 | 99.6% | 380.20 g·mol-1 | C11H15N2Na2O8P | 25 MG
β-Nicotinamide mononucleotide, reduced form (disodium) is the reduced form of β-nicotinamide mononucleotide (NMNH), an endogenous NAD+ precursor used in biochemical and cellular research. The disodium salt is supplied as a solid and is characterized for identity and purity.
- Provides the reduced NMN (NMNH) disodium salt for NAD+ metabolism studies.
- High purity suitable for analytical and cellular applications.
- Solid form with light yellow to yellow appearance.
- Storage: -20°C for solid; in solvent: -80°C up to 6 months or -20°C up to 1 month.
- Characterized by HPLC, 1H NMR, and MS to confirm identity.
Medchemexpress LLC Nicotinamide-guanine dinucleotide sodium | 2600354-60-5 | 701.41 | C21H26N7NaO15P2 | 10 MG
Nicotinamide-guanine dinucleotide sodium is a sodium salt analog of nicotinamide-guanine dinucleotide (an NAD analog) supplied as a research reagent. It functions as a coenzyme for alcohol dehydrogenase (ADH) in vitro and is provided in small laboratory pack sizes.
- Functions as a coenzyme for alcohol dehydrogenase in vitro.
- Sodium salt form suitable for biochemical assays.
- Molecular weight 701.41 and formula C21H26N7NaO15P2.
- Provided in a 10 mg research pack for laboratory use.
- Intended for research applications and enzymatic studies.
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 10 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
- Tyrosine kinase inhibitor
- Targets ITD and FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
- Available in various quantities
- Available as solid or in solution (10 mM in DMSO)
- Off-white to yellow solid appearance
- For research use only
- Has a data sheet, COA, SDS, and handling instructions available
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5 betagama imi100MG
Guanosine 5prime-[beta gamma-imido]triphosphate (GMP-PNP Gpp(NH)p) is a non-hydrolyzable analog of GTP that binds and irreversibly activates G proteins. Gpp(NH)p is used in a variety of applications that involve GTP binding including GTP-activation GTP-inhibition GTP transport GTP hydrolysis and GTP structure stabilization. Since a cycle of GTP binding hydrolysis and release is required for the initiation of protein translocation across the endoplasmic reticulum guanosine 5prime-[beta gamma-imido]triphosphate is often used in studies of protein synthesis. Gpp(NH)p is used to activate ADP-ribosylation factors and to modulate G proteins involved in cell signaling protein synthesis and other metabolic processes.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 15N5 5 triphosph10MG
Adenosine 15N5 5 triphosph10MG
Apexbio Technology LLC Lamivudine 134678-17-4 10mM (in 1mL DMSO)
Lamivudine is a nucleoside analog that acts primarily as a reverse transcriptase inhibitor disrupting viral replication by interfering with RNA-dependent DNA polymerase activity It inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with an IC50 value of approximately 0 316 M Lamivudine also suppresses replication of simian retrovirus (SRV-1 and SRV-2) while exhibiting negligible activity on foamy viruses and amphotropic murine leukemia virus (MLV-A) Due to its antiviral mechanism and dual inhibitory effect against both HIV-1 and hepatitis B virus (HBV) lamivudine is frequently utilized in research involving retroviral infection models particularly HIV-1 and HBV coinfection studies to evaluate viral dynamics antiviral efficacy and biochemical responses
Research Products International Corp 5-Bromo-2'-Deoxyuridine, 500 Milligrams
Thymidine analog used for study of DNA synthesis. This analog selectively incorporates into cellular DNA during S-phase. Supplied as white powder.
Medchemexpress LLC Nicotinic acid mononucleotide | 321-02-8 | MFCD00070358 | 98.1% | 335.2 g·mol⁻1 | C11H14NO9P | 5 MG
Nicotinic acid mononucleotide (NaMN) is a nucleotide intermediate in the biosynthesis of NAD+. It is produced from nicotinic acid via phosphoribosyltransferase and serves as a substrate for adenylyltransferases involved in NAD+ metabolism. Supplied as a research-grade reagent for biochemical and enzymatic studies.
- Intermediate in NAD+ biosynthesis and metabolism.
- Substrate for adenylyltransferase and enzymatic assays.
- High purity, typically ~98%.
- Molecular weight 335.2 g·mol⁻1; formula C11H14NO9P.
- Intended for research use only; not for human consumption.
Sigma Aldrich Fine Chemicals Biosciences 2 Deoxyadenosine monohydra25G
2 Deoxyadenosine monohydra25G
Medchemexpress LLC NAD+ (beta-Nicotinamide Adenine Dinucleotide) | 53-84-9 | 99.96% | 1 ML
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Found widely in nature, it is involved in numerous enzymatic reactions, serving as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide).
- Involved in numerous enzymatic reactions as an electron carrier
- White to off-white solid appearance
- Available in solid and solution forms